I have found that the inkjet prints are quite delicate and sensitive, especially to wet media. It sucks to be working so carefully and even so, a driplet of collage medium landing on the wrong spot and UGH, you have yourself a ruined piece.
I tried using Krylon on a sample inkjet print, and that didn't work well at all. The obnoxious fumes filled the air and for 2 hours I was annoyed at myself. On this piece, I painted on the inkjets with acrylic, and thankfully it didn't smear my prints.
I prefer to cut up the actual photos and use them, their durability is enviable. I wish I had an enlarger--enlarging the prints costs big bucks. Damn cheap artist that I am, I'll have to settle for the handspun inkjets for now.